Fildena 100 mg is a brand name medicine for the pill sildenafil citrate and is used to treat men with erectile dysfunction.
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Sildenafil without a doctors prescription There are medications how to get a registered trial of Fildena. If Fildena isn't working or isn't safe for you, talk to your doctor about other possible treatments for ED, such as: Some medications for heart conditions, such as nitroglycerin and other nitrates, can interact dangerously with Fildena and cause your blood pressure to drop.
If Fildena doesn't work after 30 minutes, don't take any more than the daily dose that your doctor prescribed. A 25-mg dose may wear off after a couple of hours, but a 100-mg dose may take nearly four times as long to leave your system. If you're not relaxed or comfortable during sex, or if you have performance anxiety because of past sexual experiences, Fildena may not last long or be fully effective.
Drinking alcohol can also decrease blood flow to your penis, making Fildena less effective or shorter-lasting. These data suggest that sufficient sildenafil remains systemically available to allow for adequate erections 4 h postdose and are consistent with a sildenafil half-life of 3-5 h 3 This is an appropriate period of therapeutic activity that is realistic and convenient for most couples. Among the sildenafil responders, the median total duration of grade 3 or 4 erections was 24.0 min (range 0-55 min), and the mean was 23.8±4.2 min, whereas the median duration for placebo responders was 0 min (range 0-23 min), and the mean was 4.8±2.5 min (P < 0.001).
When VSS commenced 2 h after dosing, the median total duration of grade 3 or 4 erections for patients receiving sildenafil was 19.5 min (range 0-55 min), and the mean duration (±s.e. mean) was 19.4±4.1 min. The median total duration of erections with >60% rigidity, as determined by RigiScan® monitoring during the 70 min after dosing, was 8.5 min (range 0-48 min) for the sildenafil recipients, compared with 0 min (range 0-16 min) for the placebo recipients. The anova showed a statistically significant treatment effect (P =0.006) and the ratio of geometric means (sildenafil:placebo) was 3.74 (95% confidence interval: 1.57, 8.94), suggesting that sildenafil increased the duration of rigidity by three- to fourfold, compared with placebo.
Sildenafil also significantly increased the duration of erections with >60% penile rigidity, compared with placebo. Eight of 17 patients (47%) responded to both sildenafil and placebo. Seven patients had received previous treatments for ED: four received prostaglandin, two yohimbine and one an investigational drug.
VSS, which lasted for 60 min, commenced 2 h after dosing with study drug during the treatment periods in part one and 4 h after dosing with study drug during the treatment periods in part two.
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